Some rare cases of higher genetic mutation rates in children, known as hypermutation, could be linked to the father receiving certain chemotherapy treatments, new research has found.
Scientists from the Wellcome Sanger Institute and their collaborators analyzed over 20,000 families’ genetic information and identified 12 children with between two to seven times more mutations than the general population.
The team linked the majority of these to increased mutations in the sperm of the biological father.